vicoprofen

DESCRIPTION

Each VICOPROFEN (hydrocodone and ibuprofen) tablet contains:

Hydrocodone Bitartrate, USP 7.5 mg

Ibuprofen, USP 200 mg

VICOPROFEN (hydrocodone and ibuprofen) is supplied in a fixed combination tablet form for oral administration. VICOPROFEN (hydrocodone and ibuprofen) combines the opioid analgesic agent, hydrocodone bitartrate, with the nonsteroidal anti-inflammatory (NSAID) agent, ibuprofen.

Hydrocodone bitartrate is a semisynthetic and centrally acting opioid analgesic. Its chemical name is: 4,5 α-epoxy-3-methoxy-17-methylmorphinan-6-one tartrate (1:1) hydrate (2:5). Its chemical formula is: C₁₈H₂₁NO₃•C₄H₆O₆•2½H₂O, and the molecular weight is 494.50. Its structural formula is:

Ibuprofen is a nonsteroidal anti-inflammatory agent [non-selective COX inhibitor] with analgesic and antipyretic properties. Its chemical name is: (±)-2-(p-isobutylphenyl) propionic acid. Its chemical formula is: C₁₃H₁₈O₂, and the molecular weight is: 206.29. Its structural formula is:

Inactive ingredients in VICOPROFEN (hydrocodone and ibuprofen) tablets include: colloidal silicon dioxide, corn starch, croscarmellose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, and titanium dioxide.